Dr. Sprague has been a nurse for 23 years. She has spent the majority of those 23 years in critical care but she has also assumed roles as an emergency room nurse, nurse auditor, PACU nurse, critical care CNS, manager in critical care, and house supervisor. Dr. Sprague was chairperson for her hospital’s sepsis committee. During this time, she worked with the Surviving Sepsis Campaign on their first collaborative. This 18-month collaborative was the first time the SSC took their sepsis initiatives to the wards. This work was published in the Journal of Hospital Medicine, titled “Implementation of a multicenter performance improvement program for early detection and treatment of severe sepsis in general medical–surgical wards”. She currently works for the Indianapolis VA Medical Center as the Patient Safety Manager where she is an active member of the sepsis committee. Dr. Sprague has spoken both locally and nationally on sepsis.